That there would be a single-point source to start the epidemic in the United States is not very likely. However, the letter O was misinterpreted as a zero in the scientific literature.
In autumnwhen the initial results of the study began to circulate in the research community, Patient zero hiv cluster was taken as powerfully suggestive evidence of an as-yet unknown virus. Once the media and the Patient zero hiv noticed the name, the damage was done. In Randy Shilts set out to write a heroes-and-villains history of the epidemic.
But the term Patient Zero had already taken off. The evidence suggests the virus came to the United States from the Caribbean. It could have even been blood products. Shilts detailed how Dugas allegedly ignored the pleas of his doctors and friends, and continued to engage in unprotected sex—supposedly only informing his partners afterward that he was sick, and that they would probably get sick, too.
Along with others, Michael Worobey, a University of Arizona professor who led the new study, has been working for years to retrace the path the virus took as it emerged from its source to fan out across the globe. Plotting them against the sequences of the other HIV viruses can help to generate a timeline for an outbreak because scientists know the rate at which the virus mutates.
He was among the first individuals reported to the Centers for Disease Control when they began investigating cancers and other immune disorders affecting gay men in — conditions we now recognize as AIDS. Briefly, in early researchers disagreed about what caused the immune disorder.
Michael Worobey conducted a genetic study that looked at blood samples taken from gay and bisexual men in and as part of a hepatitis B study, and based on the results of the data, concluded that Dugas was not the source of the virus in the U.
The information that can be gleaned from this trove of sequence information suggests the virus arrived in the US around — before Dugas became a flight attendant and began his travels. The CDC never publicly disclosed his identity, although they did share information about him with other epidemiologists and physicians who cared for him.
The samples came from men who had sex with men. Going back in time with blood For the new research, Worobey and his colleagues gathered archival blood samples in New York and San Francisco that were originally collected for a hepatitis B study in and These more likely had occurred years previously, with different sexual partners, beyond the recall of the men being interviewed or the time period focused on by the researchers.
Similar genetic clock methods have also cleared World Cup soccer tournament fans of introducing the Zika virus to the Americas, and have helped epidemiologists track foodborne outbreaks. CDC investigators interviewed a number of these early surviving cases for details about their past sexual partners.
Armed with that information, investigators at the U. Several factors then led to the Dugas-as-Patient-Zero narrative. There have been several long-lasting misconceptions about the sexual network depicted in the cluster study and about Dugas.
When you step back in time, you see a very interesting pattern. They sequenced HIV genomes from patient blood samples and examined how the virus mutated over time.In short, we found no evidence that Patient 0 was the first person infected by this lineage of HIV” Dr.
Jacques Pepin, who has also written about the origins of the AIDS epidemic, called the study “excellent work,” saying it is amazing the team was able to find relevant blood samples from the late s and harvest genetic sequences of HIV viruses from.
A new book on gay male flight attendants reveals the truth behind "Patient Zero." (JOHN MCCONNICO / The Associated Press) Gaetan Dugas, an Air Canada flight attendant vilified as "Patient Zero" in Randy Shilts' book "And The Band Played On," about the AIDS epidemic, is seen in an undated photo.
Oct 27, · A new HIV study clears the name of Gaëtan Dugas, called patient zero, and provides new insight into how the virus spread to the United States.
Dugas was code-named as "patient O" (pronounced "oh", and standing for "Out-of-California"); misconstruing of the letter "O" as 0 (zero) led to the origin of the term "patient zero."  The extent to which HIV/AIDS was known about in the early s, how it was spread, or when Dugas was diagnosed are disputed.
Oct 26, · "Patient Zero. One of the first cases of AIDS. The first person identified as the major transmitter of the disease," host Harry Reasoner said. From that point on, Tiemeyer says, Dugas became lodged in the popular consciousness as Patient Zero — the source of HIV in North America and the scapegoat for a horrific new pandemic.
HIV probably arrived in the U.S. around —a decade before AIDS was recognized as a disease and a dozen years before scientists discovered the virus that causes it—according to a new.Download